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Metachronous Osteosarcoma
by dr Zico Paradigma - Thursday, 26 October 2017, 11:47 AM
Metachronous osteosarcoma is a rare form of osteosarcoma manifested by one or more new tumors developing after the initial treatment of primary osteosarcoma (Czerniak, 2016). Metachronous osteosarcoms mainly occurs in adolescents or young adults and present as asymmetric lesions in the metaphyses of the long tubular bones. Patients with metachronous osteosarcoma have a better prognosis than other types of osteosarcoma and several cases with long-term survival were reported. Previous reports generally agreed that metachronous osteosarcoma is a potentially curable disease. The authors thought the cause of good prognosis of metachronous osteosarcoma seems to be that secondary tumor develops after adequate control of primary tumor and intervening visceral metastasis is rare (Hameed et al., 2012). However, the pathogenesis of metachronous osteosarcoma is still unknown whether metachronous osteosarcoma represent multiple true primaries or metastatic disease (Hameed et al., 2012)

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